Blocking Enzymes in Hair Follicles Promotes Hair Growth


Androgenetic alopecia (AA) or ‘male pattern baldness’ is one of the most common causes of hair loss . It can occur due to 3 main factors – genetic predisposition, presence of dihydrotestosterone (DHT) or the age factor. It is characterized by hair follicle miniaturization, i.e. the hair follicles produce thinner, shorter, more brittle hair with weaker shafts. The hair growth cycle normally consists of 3 phases, i.e. growth (anagen), cessation (catagen), and rest (telogen) phases. In AA, the hair follicles are unable to reenter the anagen or growth phase again and remain in a dormant state. Researchers at Columbia University Medical Centre have recently discovered a potential cure for AA by establishing that hair growth can be restored by an enzyme that blocks the JAK-STAT pathway in them!