Scientists use CRISPR-Cas9 to target RNA in live cells for the first time


The genetic code stored in DNA determines everything from the color of our eyes to our susceptibility to a disease. This has motivated scientists to sequence the human genome and develop ways to alter the genetic code, but many diseases are linked to a different fundamental molecule: RNA. As the intermediary genetic material that carries the genetic code from the cell’s nucleus, scientists have long sought an efficient method for targeting RNA in living cells. Researchers at University of California, San Diego School of Medicine have now achieved this by applying the popular DNA-editing technique CRISPR-Cas9 to RNA. This study was published on March 17, 2016 in Cell.