Brain Cancers Reveal Novel Genetic Disruption in DNA


Brain cancer has been extensively studied for years, yet doctors have made little progress in treating this disease. Recently, a research team led by Dr. Bradley E. Bernstein from the Broad Institute has suggested that a housekeeping gene encoding a humdrum metabolic enzyme is responsible for a series of downstream cascades that eventually lead to cells turning cancerous. This discovery suggests that long-existing small molecule chemotherapeutics might come back into use and might be powerful enough as a cure. “What this tells me is that I know a lot less than I did before,” said Dr. Jeremy Rich, a brain cancer expert at the Cleveland Clinic.