A single RNA molecule links neuroblastoma to renal carcinoma


The neuroblastoma-associated transcript 1 (NBAT1), previously known as CASC14, is a long noncoding RNA (lncRNA) molecule that is devoid of producing any functional protein. Initially, NBAT1 was found to have a plausible role in progression of neuroblastoma (NB) tumors, but more recently, a Chinese group from different universities published a paper in International Journal of Clinical and Experimental Pathology showing that NBAT1 is associated with poor prognosis in patients with clear cell renal cell carcinoma (ccRCC).