Cell therapy for heart repair


An innovative study on repairing damaged heart tissue through stem cell therapy has given a hope to patients suffering from heart disease. Heart attacks damage cardiac muscle cells or ‘cardiomyocytes’, often leading to irreversible functional damage. In earlier trials, treatment with stem cells of non-cardiac origin had limited success due to graft rejection and failure on host tissue. Researchers from the A*STAR Bioprocessing Technology Institute (BTI) have developed a method to isolate and expand human heart stem cells, also known as cardiac progenitor cells, which lead to a potential treatment option by replacing the damaged cells with new functional cardiomyocytes through stem cell therapy.