Birth-control pills or contraceptives are drugs that are used to prevent pregnancy. Traditionally, these drugs have been taken by women to mitigate the risk of unwanted pregnancy. A team led by Haruhiko Miyata of Osaka University’s Research Institute for Microbial Diseases from Japan challenged this notion by developing a novel contraceptive pill for men. Cyclosporine A (CsA) and Tacrolimus (FK506) are common immuno-suppressants that are given to patients undergoing transplant surgery, to reduce the risk of rejection. These drugs help prevent synthesis of a protein, that usually helps the T-cells to mount an attack against the body, by inhibiting an enzyme named calcineurin.